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If you are taking Femara to increase fertility, take it strictly as directed. Femara should not be taken once you have conceived. Femara is usually taken once a day or once every other day when used to treat or protect against breast cancer recurrence in postmenopausal women. Be cautious when driving or operating machinery if Femara makes you dizzy or tired. Your doctor may wish to monitor your bone mineral density (BMD) while you are taking Femara as it may lower your BMD. Research has shown that treatment with aromatase inhibitors like Femara can extend the length of time for a breast cancer recurrence or breast cancer spreading in the body. In one study, over 70% of women had a disease-free survival period for up to 8 years. Studies that have compared tamoxifen with aromatase inhibitors (AIs) such as Femara in early-stage breast cancer have shown that five years of treatment with AIs was more effective than tamoxifen at prolonging the time until a breast cancer comes back or having breast cancer spread in the body. There is also a benefit to switching to an AI after 2 or 3 years on tamoxifen or continuing an AI after 5 years of tamoxifen treatment (rather than stopping treatment altogether). However, there is no benefit to switching compared to using letrozole alone for 5 years; however, switching may be a reasonable option for patients who experience intolerable side effects with either drug. Some women may benefit from extended therapy past 5 years based on the risk of disease recurrence, side effects, and previous treatments. The American Society of Clinical Oncology (ASCO) recommends that for women on extended Femara treatment, 10 years should be the maximum duration of therapy. Deciding to extended Femara therapy should be a shared decision based on the risk of disease recurrence, drug side effects, disease status (node-positive/negative disease), and patient preference. Longer duration of Femara use has been associated with increased bone fractures and heart side effects, as well as treatment discontinuation. Treatment with Femara should be discontinued if breast cancer returns. Medicines that interact with Femara may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Femara. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Common medications that may interact with Femara include: antiandrogens, such as apalutamide aprepitant cannabidiol cimetidine citalopram clobazam clopidogrel dabrafenib echinacea HIV medications, such as darunavir, efavirenz hormones, such as estrone, ethinyl estradiol, or hydroxyprogesterone ivacaftor mifepristone oxcarbazepine St. John’s Wort tacrolimus or sirolimus thalidomide tamoxifen warfarin, legal steroid reviews. Note that this list is not all-inclusive and includes only common medications that may interact with Femara. You should refer to the prescribing information for Femara for a complete list of interactions. More about Femara (letrozole) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Espanol 57 Reviews Generic Availability Drug class: aromatase inhibitors. Patient Information Femara (Advanced Reading) Professional resources. 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Legal steroid reviews, price best steroids for sale bodybuilding drugs. Complete reduction and/or elimination of Estrogen levels often result in negative effects on the body. Female anabolic steroid users seldom need to worry about rising Estrogen levels, but for those that are competitive bodybuilders that must eliminate the water retention associated with Estrogen that causes the unwanted bloating, the use of an aromatase inhibitor such as Aromasin (Exemestane) might be necessary. It is important to remember that medically, Aromasin is approved for use in post-menopausal females only, who possess a very different shift in hormone levels compared to pre-menopausal females. Because medical data has suggested that aromatase inhibitors are far more effective in females than males (depending on the aromatase inhibitor in question used), Aromasin doses of 12. Aromasin Dosage for Increased Endogenous Testosterone Secretion and PCT (Post Cycle Therapy) It is very clear that Aromasin can increase Testosterone levels in males as demonstrated by studies. One particular study selected 12 healthy young male test subjects, and were administered random Aromasin doses of 25mg and 50mg for a 10 day period, and not only was Estrogen suppressed by a significant amount (38%), but Testosterone levels in the test subjects were observed to increase by an incredible 60%[1]. Boosting the endogenous Testosterone production in men by an impressive 60% is not the only major benefit that Aromasin possesses. Aromasin also holds additional benefits that essentially make it the ‘king’ aromatase inhibitor for the purpose of HPTA and Testosterone recovery during PCT above all other aromatase inhibitors. The stimulation of endogenous Testosterone secretion is a characteristic common of all aromatase inhibitors and is due to the fact that excess Estrogen will cause a negative feedback loop response of the HPTA to initiate Testosterone suppression. In addition to generating a considerable increase in endogenous Testosterone output, Aromasin also holds several advantages and effects over other aromatase inhibitors that do not exhibit them. For example, a common attribute of all aromatase inhibitors is the unfortunate effect of altering cholesterol levels in a very negative manner (reduction of the ‘good’ HDL cholesterol and increasing the ‘bad’ LDL cholesterol). This is due in large part to the drop in Estrogen levels, as well as the aromatase inhibitor’s actions themselves. Aromasin has demonstrated in several studies that it impacts cholesterol profiles far less than other aromatase inhibitors have, where in one particular study on cancer patients, 24 weeks of Aromasin (Exemestane) administration held no impact on cholesterol profiles[2]. Some of the same studies mentioned have also demonstrated a nil effect on cholesterol profiles from the use of Aromasin[1]. However, some other studies have displayed an alteration in cholesterol values from Aromasin administration, but that it was not as significant or as negatively impacting as other aromatase inhibitors[3]. In addition to the lack of negative effects on cholesterol profiles, Aromasin has also demonstrated in the same study that linked Aromasin to an increase in endogenous Testosterone production to also un-alter serum IGF-1 levels, which is something uncommon among aromatase inhibitors1. At its worst, it may lower IGF-1 levels slightly, which is a significant difference from all other aromatase inhibitors, and Aromasin has also been found to lower concentrations of IGF-1 binding protein-3 (a protein that binds to and inhibits IGF-1)1. This is all very good information to the anabolic steroid using athlete who wishes to recover efficiently and quickly during the PCT weeks following the termination of a cycle, as IGF-1 is very important for muscle gains. But the benefits of Aromasin do not stop there, legal steroid reviews. There is one issue with the addition of the other two aromatase inhibitors (Arimidex and Letrozole) in a PCT program that includes the use of SERMs such as Nolvadex and Clomid, which are known as absolutely essential components to a PCT program. The problem here is that Arimidex and Nolvadex both directly counteract one another. One study has demonstrated that when Arimidex is utilized with Nolvadex, Nolvadex will decrease blood plasma concentration of Arimidex (as well as Letrozole, another commonly used aromatase inhibitor)[4]. The conclusion here is that the use of Arimidex or Letrozole with Nolvadex together is a very bad idea and may work counterproductively if used together in a PCT protocol. Aromasin completely circumvents this problem, as it has been demonstrated to have no interactions what so ever with Nolvadex, unlike the other two aforementioned aromatase inhibitors. In one study, Aromasin displayed no reduced effectiveness, nor any reduced blood plasma levels when utilized with Nolvadex[5].

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