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The last step is Time-of-Flight (TOF) or Mass Spectrometer (MS) analysis of the sample. Prior to the introduction of synthetic blood doping drugs like EPO, blood transfusions were common practice among endurance athletes. Even with these drugs available the practice still persists. Blood transfusion is an effective and relatively simple method of allowing athletes to boost the number of red blood cells in their blood, improving their aerobic capacity and endurance. Blood transfusions can be classified as autologous, where the athlete receives pre-prepared doses of his/her own blood, or allogenic, where the transfused blood comes from someone else. Athletes who choose to use this method generally begin undergoing blood withdrawals several weeks before a competition, building up a supply of blood between 450 millilitres and 1800 millilitres. The plasma is returned to the body during the withdrawal while the corpuscular elements’basically the red blood cells (RBCs)’are stored. These can then be re-infused in the patient directly before or during a high-endurance event. The re-infused blood greatly increases the number of red blood cells in the blood, boosting the blood’s ability to bring oxygen to tired muscles. Blood transfusions were common practice before being banned in 1986. The first known case was Kaarlo Maaninka, who transfused two pints of blood prior to winning medals in the 1980 Olympics, peg-mgf 2 mg peptides . By the 1984 Olympics, one-third of the US cycle team received transfusions, resulting in nine medals. In 2007 Alexander Vinokourov, a rider in the Tour de France, tested positive after winning the 13 th stage of the race. His blood was found to contain two different blood cell populations, which confirmed the use of allogenic transfusions. Cheating via blood transfusions was initially difficult to catch, especially if athletes re-infused their own blood. The arrival in 2004 of a test to detect allogenic blood transfusions meant athletes could no longer use the blood of a donor, however, they could still cheat by re-infusing their own. The development of Athlete Biological Passports (see below), has made even this method more detectable, as the passports allow testers to see the indirect markers of blood doping. The risks of using blood transfusions to increase red blood cells is similar to the risks associated with EPO and SOC use: thickened blood leading to clotting, heart attack and stroke. Another risk relates to the process itself. Because transfusions involve several stages’the withdrawal of blood, its storage and re-use’there are many opportunities for something to go wrong. Contamination of the blood or equipment, infection and improper administration of blood products, all of which could easily lead to drastic health problems, even death. Blood transfusions are more widely known for saving lives, but have also been used by athletes to increase red blood cells. Image source: El Alvi / Flickr. Beta Blockers work to block the effects of adrenaline. They work to slow the heart rate, thereby reducing blood pressure, anxiety and muscle tremors, and improving the ability to focus.
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