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People who abuse anabolic steroids usually take them orally, inject them into the muscles, or apply them to the skin with a cream or gel. People misuse steroids in a variety of doses and schedules. Misuse of anabolic steroids might lead to short-term effects, including paranoid jealousy, extreme irritability and aggression, delusions, impaired judgement, and mania. Continued steroid misuse can act on some of the same brain pathways and chemicals that are affected by other drugs, including dopamine, serotonin, and opioid systems. Anabolic steroid misuse might lead to serious long-term, even permanent, health problems. Several other effects are gender- and age-specific. People who inject steroids increase their risk of contracting or transmitting HIV/AIDS or hepatitis. Even though anabolic steroids do not cause the same high as other drugs, they can lead to addiction. Some people seeking treatment for anabolic steroid addiction have found behavioral therapy and medications to be helpful. Medicines can help treat symptoms of withdrawal in some cases. For additional information about anabolic steroids, visit: Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) Research Report What are the side effects of anabolic steroid misuse? A variety of side effects can occur when anabolic steroids are misused, ranging from mild effects to ones that are harmful or even life-threatening. Most are reversible if the user stops taking the drugs. However, others may be permanent or semi-permanent. Most data on the long-term effects of anabolic steroids in humans come from case reports rather than formal epidemiological studies. Serious and life-threatening adverse effects may be underreported, especially since they may occur many years later. One review found 19 deaths in published case reports related to anabolic steroid use between 1990 and 2012; however, many steroid users also used other drugs, making it difficult to show that the anabolic steroid use caused these deaths. Steroid use has been associated with high blood pressure; 41 decreased function of the heart’s ventricles; 23,41,42 and cardiovascular diseases such as heart attacks, 43 artery damage, 44 and strokes, 45,46 even in athletes younger than 30. Steroids contribute to the development of cardiovascular disease partly by increasing the level of low-density lipoprotein (LDL) 47 and decreasing the level of high-density lipoprotein (HDL). If blood is prevented from reaching the heart or brain, the result can be a heart attack or stroke, respectively, max-one 10 mg oral steroids dianabol. Steroids also increase the risk that blood clots will form in blood vessels, potentially disrupting blood flow and damaging the heart muscle, so that it does not pump blood effectively. Steroid use disrupts the normal production of hormones in the body. Changes that can be reversed include decreased sperm production, 56’59 decreased function of the testes (hypogonadism) that leads to low testosterone levels, 60 and shrinking of the testicles (testicular atrophy). In females, anabolic steroids cause masculinization. Specifically, breast size and body fat decrease, the skin becomes coarse, and the voice deepens.
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