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One particular study selected 12 healthy young male test subjects, and were administered random Aromasin doses of 25mg and 50mg for a 10 day period, and not only was Estrogen suppressed by a significant amount (38%), but Testosterone levels in the test subjects were observed to increase by an incredible 60%[1]. Boosting the endogenous Testosterone production in men by an impressive 60% is not the only major benefit that Aromasin possesses. Aromasin also holds additional benefits that essentially make it the ‘king’ aromatase inhibitor for the purpose of HPTA and Testosterone recovery during PCT above all other aromatase inhibitors. The stimulation of endogenous Testosterone secretion is a characteristic common of all aromatase inhibitors and is due to the fact that excess Estrogen will cause a negative feedback loop response of the HPTA to initiate Testosterone suppression. In addition to generating a considerable increase in endogenous Testosterone output, Aromasin also holds several advantages and effects over other aromatase inhibitors that do not exhibit them. For example, a common attribute of all aromatase inhibitors is the unfortunate effect of altering cholesterol levels in a very negative manner (reduction of the ‘good’ HDL cholesterol and increasing the ‘bad’ LDL cholesterol). This is due in large part to the drop in Estrogen levels, as well as the aromatase inhibitor’s actions themselves. Aromasin has demonstrated in several studies that it impacts cholesterol profiles far less than other aromatase inhibitors have, where in one particular study on cancer patients, 24 weeks of Aromasin (Exemestane) administration held no impact on cholesterol profiles[2]. Some of the same studies mentioned have also demonstrated a nil effect on cholesterol profiles from the use of Aromasin[1]. However, some other studies have displayed an alteration in cholesterol values from Aromasin administration, but that it was not as significant or as negatively impacting as other aromatase inhibitors[3]. In addition to the lack of negative effects on cholesterol profiles, Aromasin has also demonstrated in the same study that linked Aromasin to an increase in endogenous Testosterone production to also un-alter serum IGF-1 levels, which is something uncommon among aromatase inhibitors1. At its worst, it may lower IGF-1 levels slightly, which is a significant difference from all other aromatase inhibitors, and Aromasin has also been found to lower concentrations of IGF-1 binding protein-3 (a protein that binds to and inhibits IGF-1)1. This is all very good information to the anabolic steroid using athlete who wishes to recover efficiently and quickly during the PCT weeks following the termination of a cycle, as IGF-1 is very important for muscle gains. But the benefits of Aromasin do not stop there. There is one issue with the addition of the other two aromatase inhibitors (Arimidex and Letrozole) in a PCT program that includes the use of SERMs such as Nolvadex and Clomid, which are known as absolutely essential components to a PCT program. The problem here is that Arimidex and Nolvadex both directly counteract one another. One study has demonstrated that when Arimidex is utilized with Nolvadex, Nolvadex will decrease blood plasma concentration of Arimidex (as well as Letrozole, another commonly used aromatase inhibitor)[4]. The conclusion here is that the use of Arimidex or Letrozole with Nolvadex together is a very bad idea and may work counterproductively if used together in a PCT protocol. Aromasin completely circumvents this problem, as it has been demonstrated to have no interactions what so ever with Nolvadex, unlike the other two aforementioned aromatase inhibitors. In one study, Aromasin displayed no reduced effectiveness, nor any reduced blood plasma levels when utilized with Nolvadex[5]. Nolvadex is also very well known for reducing blood plasma levels of IGF-1 during use[6]. This might possibly indicate that Aromasin may assist to maintain stable IGF-1 levels or at the very least do nothing to further worsen Nolvadex’s effects on IGF-1, legal steroids nz. Therefore, from all of the information gathered, Aromasin and Nolvadex when utilized together for PCT are very complimentary with one another, making Aromasin the absolute best aromatase inhibitor not only for general use but also for HPTA recovery during PCT (or at any other time). A sufficient Aromasin dosage for HPTA recovery during PCT would be 25mg daily for no longer than a 2 week period while Nolvadex would be utilized for a total of 4 weeks at 20 ‘ 40mg daily. Proper Administration and Timing of Aromasin Dosages.
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